Azelastine is a potent antihistamine primarily used to treat allergic rhinitis and conjunctivitis, often marketed under brand names like Astelin and Optivar. It works by blocking histamine H1 receptors, thereby relieving symptoms like sneezing, nasal congestion, and itchy eyes without causing significant drowsiness. Ensuring the pharmaceutical purity of Azelastine is essential for maintaining its therapeutic effectiveness, minimizing adverse reactions, and meeting regulatory standards. Impurity profiling plays a vital role in identifying and controlling unwanted substances formed during manufacturing, storage, or degradation. Here are some of its known impurities listed below.
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Catalogue No : AZEL-OCL-001
CAS No : 20526-97-0
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Synonyms
Azelastine USP RC E 3-(4-Chlorobenzylidene)isobenzofuran-1(3H)-one 3-(4-Chlorobenzal)phthalide
Azelastine USP RC E 3-(4-Chlorobenzylidene)isobenzofuran-1(3H)-one 3-(4-Chlorobenzal)phthalide