Bumetanide is a potent loop diuretic primarily used to treat edema associated with congestive heart failure, liver disease, or kidney disorders. It works by inhibiting sodium and chloride reabsorption in the ascending loop of Henle, promoting fluid excretion. Due to its strong diuretic effect, maintaining the pharmaceutical purity of Bumetanide is essential for ensuring patient safety, drug effectiveness, and adherence to regulatory standards. Impurity profiling aids in detecting and managing unwanted substances that may arise during synthesis, storage, or degradation. Here are some of its known impurities listed below.
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Catalogue No : BUME-OCL-001
CAS No : 28328-53-2
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Synonyms
metanide USP RC B 3-Nitro-4-phenoxy-5-sulfamoylbenzoic acid 3-(Aminosulfonyl)-5-nitro-4-phenoxy-benzoic Acid
metanide USP RC B 3-Nitro-4-phenoxy-5-sulfamoylbenzoic acid 3-(Aminosulfonyl)-5-nitro-4-phenoxy-benzoic Acid