Fosinopril is an angiotensin-converting enzyme (ACE) inhibitor primarily used to manage hypertension and heart failure by relaxing blood vessels and reducing blood pressure. It functions by inhibiting the conversion of angiotensin I to the vasoconstrictor angiotensin II, thereby easing cardiac workload. Maintaining the pharmaceutical purity of Fosinopril is essential to ensure its therapeutic effectiveness, minimize adverse effects, and comply with regulatory standards. Impurity profiling plays a key role in detecting and controlling unwanted substances that may arise during manufacturing, storage, or degradation. Here are some of its known impurities listed below.
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