Nortriptyline is a tricyclic antidepressant (TCA) primarily prescribed for the treatment of major depressive disorder and certain chronic pain conditions. It works by inhibiting the reuptake of norepinephrine and, to a lesser extent, serotonin, thereby enhancing mood-regulating neurotransmitter activity in the brain. Maintaining the pharmaceutical purity of Nortriptyline is essential to ensure patient safety, therapeutic effectiveness, and adherence to regulatory standards. Impurity profiling is crucial to detect and control any unwanted substances that may arise during its synthesis, storage, or degradation. Here are some of its known impurities listed below.
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Catalogue No : NOTR-OCL-001
CAS No : 1210-35-1
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Synonyms
Dibenzosuberone Amitriptyline EP Impurity A Amitriptyline USP RC A 10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one
Dibenzosuberone Amitriptyline EP Impurity A Amitriptyline USP RC A 10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one