Triamterene is a potassium-sparing diuretic commonly used to treat edema and hypertension, often in combination with other diuretics to minimize potassium loss. It works by inhibiting sodium reabsorption in the kidneys, which helps retain potassium while promoting the excretion of water and sodium. Maintaining the pharmaceutical quality of Triamterene is essential to ensure its therapeutic effectiveness, minimize side effects, and comply with regulatory standards. Impurity profiling plays a crucial role in identifying and controlling any unwanted substances formed during synthesis, storage, or degradation. Here are some of its known impurities listed below.
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Catalogue No : TRIA-OCL-001
CAS No : 1006-23-1
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Synonyms
Triamterene USP RC A Nitrosotriaminopyrimidine 5-Nitrosopyrimidine-2,4,6-triamine
Triamterene USP RC A Nitrosotriaminopyrimidine 5-Nitrosopyrimidine-2,4,6-triamine