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Trimethoprim Impurities

Trimethoprim is an antibacterial agent widely used in combination with sulfamethoxazole to treat a variety of bacterial infections, including urinary tract infections and respiratory infections. It works by inhibiting bacterial dihydrofolate reductase, an enzyme crucial for DNA synthesis. Maintaining the pharmaceutical purity of Trimethoprim is essential to ensure its safety, therapeutic effectiveness, and adherence to regulatory standards. Impurity profiling is vital to detect and control any unwanted substances that may arise during synthesis, storage, or degradation. Here are some of its known impurities listed below.

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Trimethoprim impurity J
Catalogue No : TRIE-OCL-001

CAS No : 118-41-2

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Synonyms
Eudesmic Acid 3,4,5-Trimethoxybenzoic acid