Esomeprazole is a proton pump inhibitor (PPI) widely used to treat acid-related gastrointestinal conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. It works by blocking the H⁺/K⁺-ATPase enzyme in the stomach lining, thereby reducing acid production. Maintaining the pharmaceutical purity of Esomeprazole is essential for ensuring its therapeutic effectiveness, minimizing adverse effects, and meeting regulatory standards. Impurity profiling is crucial to detect and control unwanted substances that may arise during manufacturing, storage, or degradation. Here are some of its known impurities listed below.
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