Nifedipine is a calcium channel blocker commonly used in the management of hypertension and angina, marketed under various brand names such as Adalat and Procardia. It works by relaxing blood vessels and improving blood flow, thereby reducing blood pressure and cardiac workload. Ensuring the pharmaceutical purity of Nifedipine is essential for maintaining its therapeutic effectiveness, minimizing adverse effects, and meeting regulatory standards. Impurity profiling plays a key role in detecting and controlling unwanted substances that may form during manufacturing, storage, or degradation. Here are some of its known impurities listed below.
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