Ampicillin Impurities

Ampicillin is a broad-spectrum beta-lactam antibiotic widely used to treat various bacterial infections, including respiratory, urinary tract, and gastrointestinal infections. It works by inhibiting bacterial cell wall synthesis, making it effective against both Gram-positive and some Gram-negative bacteria. Maintaining the pharmaceutical purity of Ampicillin is essential to ensure its therapeutic effectiveness, minimize adverse effects, and meet regulatory standards. Impurity profiling is crucial to detect and control degradation products or synthesis-related by-products that may compromise safety or efficacy. Here are some of its known impurities listed below.

Ampicillin

Catalogue No : AMPI-OCL-001

CAS No : 69-53-4

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Synonyms
(2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

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Ampicillin EP Impurity A

Catalogue No : AMPI-OCL-002

CAS No : N/A

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Synonyms
(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]-heptane-2-carboxylic Acid

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Ampicillin EP Impurity D

Catalogue No : AMPI-OCL-003

CAS No : 32746-94-4

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Synonyms
(4S)-2-[[[(2R)-2-Amino-2-phenylacetyl]amino] carboxymethyl]-5,5-dimethylthiazolidine-4-carboxylic acid

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Ampicillin EP Impurity G

Catalogue No : AMPI-OCL-004

CAS No : 31485-02-6

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Synonyms
(3R,6R)-3,6-Diphenylpiperazine-2,5-dione

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Ampicillin EP Impurity H

Catalogue No : AMPI-OCL-005

CAS No : 2882-18-0

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Synonyms
3-Phenylpyrazin-2-ol

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Ampicillin EP Impurity K

Catalogue No : AMPI-OCL-006

CAS No : 40610-41-1

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Synonyms
(2R)-2-[(2,2-Dimethylpropanoyl)amino]-2-phenylacetic acid

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Ampicillin EP Impurity L

Catalogue No : AMPI-OCL-007

CAS No : 875-74-1

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Synonyms
(2R)-2-Amino-2-phenylacetic acid

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