Bosentan Impurities

Bosentan is an endothelin receptor antagonist primarily used to treat pulmonary arterial hypertension (PAH) by helping to relax and widen blood vessels, improving blood flow and reducing blood pressure in the lungs. It works by blocking the effects of endothelin-1, a substance that causes blood vessels to constrict. Ensuring the pharmaceutical purity of Bosentan is essential for maintaining its therapeutic effectiveness, minimizing adverse effects, and meeting regulatory standards. Impurity profiling is crucial for detecting and controlling unwanted substances that may arise during synthesis, storage, or degradation. Here are some of its known impurities listed below.

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