Carbidopa is a peripheral dopa-decarboxylase inhibitor commonly used in combination with Levodopa for the treatment of Parkinson's disease, helping to enhance Levodopa’s effectiveness by preventing its premature conversion to dopamine outside the brain. By doing so, it increases dopamine availability in the central nervous system while reducing side effects like nausea. Maintaining the pharmaceutical purity of Carbidopa is essential to ensure therapeutic efficacy, minimize adverse effects, and comply with regulatory standards. Impurity profiling is crucial to detect and control any undesirable substances generated during its manufacturing or storage. Here are some of its known impurities listed below.
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Catalogue No : CARB-OCL-008
CAS No : 28860-95-9
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Synonyms
(2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid monohydrate
(2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid monohydrate

Catalogue No : CARB-OCL-001
CAS No : 38821-49-7
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Synonyms
(2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid monohydrate
(2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid monohydrate

Catalogue No : CARB-OCL-002
CAS No : N/A
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Synonyms
(2S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid hydrate
(2S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid hydrate

Catalogue No : CARB-OCL-003
CAS No : 18181-08-3
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Synonyms
Methyl (2S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoate
Methyl (2S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoate

Catalogue No : CARB-OCL-004
CAS No : 52514-63-3
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Synonyms
Methyl (2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoate
Methyl (2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoate

Catalogue No : CARB-OCL-005
CAS No : 91908-71-3
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Synonyms
Ethyl (2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoate
Ethyl (2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoate

Catalogue No : CARB-OCL-006
CAS No : 158190-23-9
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Synonyms
Methyl 2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoate
Methyl 2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoate

Catalogue No : CARB-OCL-007
CAS No : 302-53-4
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Synonyms
3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid